Well Child Immunity Support Chewable is an immunity-boosting multivitamin delivered in a kid-friendly chewable form. It helps with mobilizing and maintaining immune defenses in times of need through a blend of different key natural ingredients which includes kudzu root extract.
Kudzu extract treatment does not increase the intoxicating effects of acute alcohol in human volunteers. Kudzu for alcoholism seems to be a new and relatively safe option for those struggling. According to the research and the experiences of those that have utilized the natural ingredient, kudzu seems to ease some of the side effects and help with curbing urges to drink. It is important to follow up with your health care providers if you are having issues with alcohol consumption to see their recommendations and follow their advice. However, if kudzu seems to be a burgeoning helpful natural root that could help many.
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Puerarin, one of the most abundant isoflavones in kudzu root extracts, is a known vasodilator and is approved for such use in China following coronary infarction and stroke (Wu et al., 2014). In spite of the compelling preclinical and clinical evidence of its efficacy, the precise mechanism of action of kudzu in reducing alcohol consumption is not currently known. Prior studies of its antidipsotropic effect have focused on taste-aversion, alterations in alcohol metabolism or effects on neurotransmitters. Overstreet et al.’s study provides cursory evidence that a taste aversion mechanism is not likely. Increases in 5-HIAL have been shown to be correlated with decreased alcohol consumption in hamsters (Keung et al., 1995). Kudzu’s alteration of alcohol consumption may be through direct effects at brain benzodiazepine receptors on the GABAA complex. This is the first demonstration that a single dose of kudzu extract quickly reduces alcohol consumption in a binge drinking paradigm.
This article describes some natural treatments to support AUD treatment. kudzu extract for alcoholism It also explains why it’s important to find effective treatments.
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Each subject was interviewed in person and determined to be actively drinking on a regular basis, all exceeding what would be considered normal consumption ranging from 1-2 times per week to drinking on a daily basis. Several of the subjects had been drinking for many years and often drank to or past the point of inebriation. Final inclusion of subjects was based on completing the AUDIT questionnaire that demonstrated either hazardous levels of drinking or alcohol dependence.
The kudzu extract diadzein has been isolated as an aldehyde dehydrogenase 2 (ALDH-2) inhibitor, which has been shown in animal models to reduce excessive drinking. Synthetic versions of this selective ALDH-2 inhibitor are being investigated as potential medications to suppress relapse in abstinent alcoholics. More clinical trials will need to be conducted to better understand the efficacy of kudzu extracts or synthetic variants for treatment of alcohol dependence. Participants were randomized on a blind basis to receive either 4 capsules of the extract or placebo 2.5 hours before the start of an afternoon drinking session. This pretreatment time was selected based on our pharmacokinetic study of puerarin absorption and elimination (Penetar et al., 2006). One of the ancillary factors in alcohol dependence is blood sugar imbalances. In fact our laboratory hypothesized that one such genetic factor that influences behavior including drug and food seeking is a predisposition to glucose craving and the overall effect of dopaminergic activity in the reward center of the brain.